Table 8.
GO Biological processes associated with the novel hub genes
| Novel hub genes | GO Biological Process | GO Terms |
|---|---|---|
| MAGED1 | Regulation of transcription, DNA-templated | GO:0006355 |
| Regulation of transcription from RNA polymerase | GO:0006357 | |
| II promoter | ||
| Circadian regulation of gene expression | GO:0032922 | |
| Regulation of circadian rhythm | GO:0042752 | |
| Regulation of apoptotic process | GO:0042981 | |
| Positive regulation of apoptotic process | GO:0043065 | |
| Positive Regulation of MAP kinase activity | GO:0043406 | |
| Negative regulation of transcription, DNA-templated | GO:0045892 GO:0045893 |
|
| Positive regulation of transcription, DNA-templated Neurotrophin TRK receptor signaling pathway |
||
| AP3B2 | Intracellular protein transport | GO:0006886 |
| Post-Golgi vesicle-mediated transport | GO:0006892 | |
| Anterograde axon cargo transport | GO:0008089 | |
| Anterograde synaptic vesicle transport | GO:0048490 | |
| STXBP1 | platelet degranulation | GO:0002576 |
| energy reserve metabolic process | GO:0006112 | |
| vesicle docking involved in exocytosis | GO:0006904 | |
| synaptic transmission | GO:0007268 | |
| neurotransmitter secretion | GO:0007269 | |
| neuromuscular synaptic transmission | GO:0007274 | |
| axon target recognition | GO:0007412 | |
| regulation of synaptic vesicle priming | GO:0010807 | |
| glutamate secretion | GO:0014047 | |
| protein transport | GO:0015031 | |
| AF1Q | Positive regulation of apoptotic process | GO:0043065 |
| Positive regulation of transcription, DNA-templated | GO:0045893 | |
| Positive regulation of mitochondrial depolarization | GO:0051901 | |
| Positive regulation of release of cytochrome c from mitochondria | GO:0090200 | |
| Extrinsic apoptotic signaling pathway | GO:0097191 | |
| Intrinsic apoptotic signaling pathway | GO:0097193 | |
| GASP | Endosome to lysosome transport | GO:0008333 |
| G-protein coupled receptor catabolic process | GO:1,990,172 | |
| G-protein coupled receptor catabolic process | GO:1,990,172 | |
| C14ORF78 | Plasma membrane repair | GO:0001778 |
| MAN1C1 | Protein N-linked glycosylation | GO:0006487 |
| Protein N-linked glycosylation via asparagine | GO:0018279 | |
| Post-translational protein modification | GO:0043687 | |
| Cellular protein metabolic process | GO:0044267 | |
| HNRPC | mRNA splicing, via spliceosome | GO:0000398 |
| Osteoblast differentiation | GO:0001649 | |
| RNA splicing | GO:0008380 | |
| Gene expression | GO:0010467 | |
| ATP-dependent chromatin remodeling | GO:0043044 | |
| 3′-UTR-mediated mRNA stabilization | GO:0070935 |