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. 2017 Sep 12;15:191. doi: 10.1186/s12967-017-1294-5

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© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — KEGG pathways of the upregulated and downregulated DEGs in nonprogressors. a, b The 15 most significantly upregulated pathways and 15 most significant downregulated pathways of whole blood. c, d The 15 most significantly upregulated and 15 most downregulated pathways of CD4⁺ T cells. e, f The 15 most significantly upregulated and 15 most downregulated pathways of CD8⁺ T cells. p < 0.05 and FDR < 0.01 were used as the threshold for KEGG pathway assignment