Table 1.
Africa Health Research Institute Resistance Cohort | Mochudi Prevention Project | Rakai Community Cohort Study | MRC/UVRI Uganda | |
---|---|---|---|---|
Number of sequences | 92 | 359 | 2,833 | 701 |
Number of individuals | 92 | 351 | 2,820 | 694 |
Sex, % | ||||
F | 73 | 73 | 56 | 51 |
M | 27 | 24 | 44 | 32 |
Missing | 0 | 3 | 0 | 16 |
Age at time of sampling, % | ||||
<25 | 10 | 17 | 25 | 11 |
25–29 | 20 | 21 | 28 | 13 |
30–34 | 16 | 18 | 22 | 20 |
35–39 | 24 | 14 | 15 | 19 |
40 or older | 30 | 24 | 10 | 15 |
Missing | 0 | 6 | 0 | 23 |
Serum/plasma HIV-1 RNA within 1 year of sampling date (copies/ml), % | ||||
<10,000 | 7 | 30 | 19 | 1 |
10,000–49,999 | 36 | 22 | 8 | 0 |
50,000–99,999 | 13 | 16 | 3 | 1 |
100,000 or higher | 35 | 19 | 2 | 2 |
Missing | 9 | 13 | 68 | 96 |
Self-reported ART use before sampling, % | ||||
Yes | 100 | 3 | 6 | 0 |
No | 0 | 91 | 94 | 90 |
Missing | 0 | 6 | 0 | 10 |
Year of sampling, % | ||||
2009 | 0 | 0 | 0 | 35 |
2010 | 0 | 38 | 0 | 5 |
2011 | 55 | 36 | 25 | 0 |
2012 | 42 | 17 | 46 | 0 |
2013 | 2 | 7 | 19 | 40 |
2014 | 0 | 0 | 11 | 10 |
Missing | 0 | 2 | 0 | 10 |
HIV-1 subtype, % | ||||
A1 | 0 | 0 | 19 | 23 |
B | 0 | 0 | 0 | 2 |
C | 94 | 93 | 3 | 1 |
D | 0 | 0 | 30 | 21 |
Other | 0 | 0 | 0 | 1 |
potentially recombinanta | 6 | 3 | 33 | 38 |
<500 nt to determine subtype | 0 | 4 | 15 | 14 |
As identified with the COMET HIV-1 subtyping tool52 on four partial amplicon sequences, see Materials and Methods. More refined approaches are underway to confirm recombinant sequences among potentially recombinant sequences.