Table 5.

Comparison of results from various regression approaches for visual field data from 40 randomly selected patients tested for glaucoma (n=40 patients; 80 eyes)

Variable	Standard linear regression model for both eyes		Standard linear regression model for worse eye§		Mixed model, random intercept (unstructured or compound symmetry)		Marginal model: PROC MIXED with REPEATED: unstructured		Marginal model: GEE, working independence		Marginal model: GEE, compound symmetry
	Regression coefficient (SE)	P-value	Regression coefficient (SE)	P-value	Regression coefficient (SE)	P-value	Regression coefficient (SE)	P-value	Regression coefficient (SE)	P-value	Regression coefficient (SE)	P-value
Age (per year)	0.17 (0.46)	0.71	0.16 (0.70)	0.82	0.11 (0.55)	0.85	0.03 (0.48)	0.95	0.17 (0.54)	0.76	0.11 (0.52)	0.83
Female sex	7.55 (4.17)	0.07	7.16 (6.63)	0.29	7.05 (5.02)	0.17	6.45 (4.46)	0.16	7.55 (5.03)	0.13	7.06 (4.93)	0.15
Hypertension – (yes)	−7.77 (4.10)	0.06	−0.66 (6.42)	0.92	−7.89 (4.97)	0.12	−10.7 (4.43)	0.02	−7.77 (4.70)	0.10	−7.89 (4.76)	0.10
Aphakic	−14.5 (6.3)	0.03	−16.9 (9.0)	0.07	−11.7 (6.1)	0.06	−7.72 (5.12)	0.14	−14.5 (7.1)	0.04	−11.7 (8.0)	0.14
% acuity loss (per %)	−0.70 (0.22)	0.002	−0.64 (0.32)	0.06	−0.61 (0.22)	0.009	−0.66 (0.19)	0.001	−0.70 (0.21)	0.0008	−0.61 (0.19)	0.001

^§From the eye with worse visual field.

GEE, generalized estimating equation; SE, standard error