Fig 3. Blood flow quantification for C57BL/6J and CD1 mice at baseline and 24 hours post-pMCAo as a percent of baseline flow.

A, At baseline, C57BL/6J treated, untreated and surgical control groups were equivalent, but at 24 hours post-pMCAO, treated subjects were equivalent to untreated subjects and had significantly reduced blood flow within the MCA. Surgical controls maintained baseline levels of flow at 24 hours. B, Similar to C57BL/6J mice, CD1 treated and untreated subjects were equivalent and had significant reductions in blood flow at 24 hours, while surgical controls maintained baseline levels of flow at this time point. (** = p ≤ 0.01, *** = p ≤ 0.001).