Table 3. Changes of clinical and laboratory parameters of the two groups during 12 months.

Variables	Months	E-HD	C-HD	P Value
Body weight (kg)	Baseline	56.2±10.5	56.5±11.7
	6	56.5±10.8	56.5±11.4
	12	56.6±11.0	56.5±11.9	0.99
Pre-dialysis SBP (mmHg)	Baseline	152.1±24.5	154.4±24.6
	6	147.1±26.0	147.8±22.7
	12	152.5±26.0	154.3±20.3	0.96
Pre-dialysis DBP (mmHg)	Baseline	79.1±15.0	80.0±13.6
	6	76.9±14.7	75.5±14.3
	12	78.7±14.7	78.2±12.3	0.69
Post-dialysis SBP (mmHg)	Baseline	134.6±23.7	143.4±22.2
	6	131.2±20.6	140.9±25.7
	12	134.7±22.0	139.5±21.8	0.19
Post-dialysis DBP (mmHg)	Baseline	73.5±13.5	76.4±13.1
	6	71.6±12.9	74.2±14.5
	12	72.9±12.7	73.2±12.7	0.19
WBC counts (/μL)	Baseline	5851.9±1765.2	5492.6±1711.6
	6	5782.7±1958.4	5437.0±1817.7
	12	5528.8±1757.8	5400.0±1627.6	0.35
Hemoglobin (g/dL)	Baseline	11.1±1.2	10.7±1.1
	6	11.0±1.0	10.6±1.2
	12	10.8±1.2	10.4±1.2	0.82
Serum albumin (g/dL)	Baseline	3.7±0.3	3.7±0.3
	6	3.6±0.3	3.7±0.3
	12	3.7±0.3	3.7±0.3	0.11
BUN (mg/dL)	Baseline	69.1±15.7	67.8±15.7
	6	67.3±16.3	65.0±15.0
	12	64.9±15.3	66.3±13.7	0.11
Serum creatinine (mg/dL)	Baseline	10.7±3.0	10.8±2.6
	6	10.6±2.7	11.1±2.5
	12	10.9±2.8	10.9±2.4	< 0.01
Beta 2 microglobulin (mg/L)	Baseline	26.6±6.3	27.7±7.4
	6	26.9±5.9	28.2±6.7
	12	27.6±6.2	27.4±6.5	< 0.01
C reactive protein (mg/dL)	Baseline	0.10 (0.05, 0.29)	0.10 (0.05, 0.28)	0.70
	6	0.11 (0.11, 0.37)	0.09 (0.05, 0.21)	0.08
	12	0.13 (0.13, 0.45)	0.10 (0.05, 0.33)	0.07

Values are expressed as mean ± SD, or median (interquartile range), as appropriate. E-HD, electrolyzed water HD; C-HD, conventional HD; SBP, systolic BP; DBP, diastolic BP; WBC, white blood cell; E, E-HD; C, C-HD.

Changes of C reactive protein are compared in respective months by Mann-Whitney U test, and others are compared between E-HD and C-HD by two-way repeated-measure ANOVA.