Figure 2. Remodeling of resistance pulmonary artery (PA) ring smooth muscle layers of intrauterine growth retardation (IUGR)-hypoxia and control-hypoxia rats. A, Representative immunohistochemical staining images of smooth muscle layers of resistance PAs. Brown indicates α-SMA (smooth muscle actin). Scale bar=20 µm. B, Summary histogram of immunohistochemical staining images of the smooth muscle layer of all groups. The smooth muscle layer of resistance PA rings is thicker in IUGR rats than in control rats after 2 weeks of hypoxia. Data are reported as means±SD. *P<0.05 (ANOVA).
