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(A) Kaplan–Meier survivor functions for each treatment group. (B) Pairwise comparisons of survival showing HRs (adjusted for stage and performance status) with two-sided 95% CIs (solid line) for assessment of difference (compare either end against HR = 1) and one-sided 95% CIs (dashed line) for assessment of non-inferiority (compare upper values against HR = 1.2).
