Table 3.

Multivariate analysis for prediction of Death (online supplement)

	Basic Model: Adjusted for sex and age			Fully-adjusted Model: All covariates
	Hazard Ratio	95% CI	P value	Hazard Ratio	95% CI	P value
sTPD
Q2 vs Q1	1.52	1.24–1.86	<0.001	1.18	0.97–1.45	0.105
Q3 vs Q1	2.30	1.9–2.78	<0.001	1.46	1.2–1.78	<0.001
Q4 vs Q1	3.56	2.95–4.3	<0.001	1.77	1.44–2.18	<0.001
		Linear trend	<0.001		Linear trend	<0.001
sTPD AC
Q2 vs Q1	1.26	1.04–1.53	0.021	1.12	0.92–1.36	0.274
Q3 vs Q1	2.00	1.67–2.4	<0.001	1.44	1.2–1.74	<0.001
Q4 vs Q1	3.05	2.56–3.63	<0.001	1.65	1.36–2.01	<0.001
		Linear trend	<0.001		Linear trend	<0.001
iTPD
Q2 vs Q1	0.95	0.78–1.15	0.580	0.95	0.78–1.16	0.612
Q3 vs Q1	1.32	1.15–1.53	<0.001	1.07	0.93–1.24	0.355
Q4 vs Q1	1.63	1.42–1.88	<0.001	1.25	1.08–1.44	0.003
		Linear trend	<0.001		Linear trend	0.003
iTPD AC
Q2 vs Q1	1.26	1.06–1.5	0.011	1.07	0.9–1.29	0.432
Q3 vs Q1	1.72	1.45–2.03	<0.001	1.21	1.01–1.43	0.034
Q4 vs Q1	1.98	1.69–2.34	<0.001	1.35	1.14–1.61	<0.001
		Linear trend	<0.001		Linear trend	<0.001