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. Author manuscript; available in PMC: 2018 Sep 1.
Published in final edited form as: Brain Res Bull. 2017 Jun 23;134:38–46. doi: 10.1016/j.brainresbull.2017.06.016

Fig. 5. αCT1 reduces Cx43 protein expression.

Fig. 5

(a–b) Using Western blot analysis we find a significant reduction in Cx43 expression at 24 hours post-αCT1 treatment compared to Reverse. Quantified expression of Cx43 is graphed relative to β-actin levels. Although overall pS368 is reduced, the expression relative to the total levels of Cx43 is increased following 150 μm αCT1 exposure compared to 150 μm Reverse. (c–d) Expression of p-Akt (relative to total Akt) and Bcl-2 (relative to β-actin) show a trend towards reduced levels in αCT1 compared to Reverse. ***P<0.001 compared to Reverse control peptide.