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. 2017 Sep 13;7:11472. doi: 10.1038/s41598-017-11815-8

Figure 6.

Figure 6

Renal cortical expression of p-p38 (a–d) and p-JNK (e–h) MAPKs in the renal cortex of the control (a,e), control + calcitriol (b,f), losartan (c,g), and losartan + calcitriol (d,h) groups. The number of p-p38-positive cells (i) and score for p-JNK (n) in the renal cortex. Scale bar = 50 μm. Western blot analysis of p-p38 and PCNA (j,l) in renal cortex from control (lane 1), control + calcitriol (lane 2), losartan (lane 3) and losartan + calcitriol (lane 4) groups. Densitometry of p-p38 and PCNA (k,m). A densitometric ratio between the densitometry of p-p38 or PCNA and α1-tubulin was calculated and data are expressed in comparison to the control, with the mean (±SEM) control value designated as 100%. Blots are representative images from independent experiments (n = 5–6 for each group). Data are expressed as median and interquartile range (25th–75th) (n) or mean ± SEM (i,k,m). n = 7–12 animals per group. *P < 0.05,**P < 0.01 and ***P < 0.001 vs. control; # P < 0.05, ## P < 0.01 and ### P < 0.001 vs. control + calcitriol; and § P < 0.05, and §§ P < 0.01 vs. losartan.