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. 2017 Sep 13;7:11491. doi: 10.1038/s41598-017-09250-w

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Connectome resolution and anatomical reliability as function of data and method. (a) Scatter plot of number of found fascicles and global r.m.s error in LiFE_T optimized connectomes (mean ±5 standard error of the mean, s.e.m., N = 1,490, n = 12 subjects, m = 10 repeated tracking, using either 13 or 9 different L _max values for either STN, HCP3T or HCP7T). Inset shows the relation between the number of found fascicles (ordinate) and r.m.s. error (abscissa) and L _max (color) in one subject from the HCP3T dataset. (b) Reproducibility of connectome anatomy. Twenty major human white matter tracts, two repeated estimates in a single subject probabilistic (top) and deterministic (bottom) tracking, HCP3T dataset. Tracts anatomy is very similar between repeated estimates when using a single tracking method (compare between columns, top and bottom). Estimated tracts anatomy differs within a single subject when the different tracking methods are used (compare between rows, left or right). (c) A different subject from the HCP3T dataset.