Table 1.
Description of sites, reagents and instruments used in the multicenter study.
| Site | Company | Method | Assay principle | Sample volume (µL) | Measuring range (ng/mL) |
|---|---|---|---|---|---|
| Parma, Italy | BRAHMS, Hennigsdorf, Germany | Kryptor BRAHMS PCT sensitive | Time-Resolved Amplified Cryptate Emission (TRACE) immunoassay | 50 | 0.02–1000 |
| Asti, Italy | Diasorin, Saluggia (VC), Italy | Liaison BRAHMS PCT | Two-site immunoluminometric assay | 100 | 0.02–100 |
| Lodi, Italy | bioMérieux, Marcy l’Etoile, France | Vidas BRAHMS PCT | Enzyme-linked fluorescent immunoassay (ELFA) | 200 | 0.05–200 |
| Milano, Italy | Roche Diagnostics, Mannheim, Germany | Roche BRAHMS PCT | Electrochemiluminescence immunoassay (ECLIA) | 30 | 0.02–100 |
| Alessandria, Italy | Siemens Diagnostics, Marburg, Germany | Siemens BRAHMS PCT | One-step chemiluminescence immunoassay | 100 | 0.02–75 |
| Bassano del Grappa, Italy | Abbott Diagnostics Abbott Park, Illinois, U.S.A | Diazyme procalcitonina | Latex-enhanced immunotubidimetric assay | 20 | 0.16–56 |
| Alessandria, Italy | Siemens Healthcare Diagnostics, Marburg, Germany | Diazyme procalcitonina | Latex-enhanced immunotubidimetric assay | 20 | 0.16–56 |
| Milano, Italy | Roche Diagnostics, Mannheim, Germany | Diazyme procalcitonina | Latex-enhanced immunotubidimetric assay | 20 | 0.16–56 |
| Parma, Italy | Beckman Coulter Inc., Brea, CA, USA | Diazyme procalcitonina | Latex-enhanced immunotubidimetric assay | 20 | 0.16–56 |
a
Diazyme procalcitonin, Diazyme Laboratories, Poway, CA, USA.