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. 2017 Apr 7;12(8):1284–1295. doi: 10.1093/scan/nsx050

Table 3.

Brain regions exhibiting significant differences in RSFC with the abnormal FCD regions (in italic) between the SAD and HC groups

Regions Side BA t Size MNI
x y z
Right rACC
    SAD >HC None
    SAD <HC
    Cluster 1 STG R 21 5.73 105 69 −12 −6
    Cluster 2 Precuneus/MCC R/L 7/31 5.59 426 0 −30 48
    Cluster 3 SFGa L 9 4.82 35 −18 45 36
    Cluster 4 MFGa R 6/8 4.47 58 30 15 60
    Cluster 5 SFGa R 10 4.21 45 15 63 18
Right STG
    SAD >HC None
    SAD <HC
    Cluster 1 STG L 43/41/22/42 5.34 344 −54 −12 9
    Cluster 2 Insula R 13/21/22 5.02 262 33 6 6
Putamen R
    Cluster 3 STGa R 42/43/21/21 4.97 385 66 −18 9
    Cluster 4 PTCG/PRCG R 4/6/3 4.52 180 51 −18 54
    Cluster 5 Middle TPO R 38 4.33 26 30 15 −39
    Cluster 6 PRCG/PTCG L 4/6 4.30 97 −42 −15 54
    Cluster 7 SMA L 6/24 3.93 44 −3 −6 54
    Cluster 8 IFG R 46 3.88 57 30 27

Coordinates refer to the local peak within each cluster. Results were thresholded at FDR < 0.05, K > 20. rACC, rostral anterior cingulate cortex; STG, superior temporal gyrus; MCC, middle cingulate cortex; SFG, superior frontal gyrus; MFG, middle frontal gyrus; PTCG, postcentral gyrus; PRCG, precentral gyrus; TPO, temporal pole; SMA, supplementary area; IFG, inferior frontal gyrus. BA, Broadmann area; MNI, Montreal Neurological Institute; L, left hemisphere; R, right hemisphere; SAD, social anxiety disorder; HC, healthy control.

a

RSFC between these regions and the abnormal FCD regions contributed most substantially to SAD diagnosis