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. Author manuscript; available in PMC: 2018 Jan 1.
Published in final edited form as: J Toxicol Environ Health A. 2017;80(1):53–68. doi: 10.1080/15287394.2016.1238329

Figure 7. Nano vs. fine particles-induced cell death.

Figure 7

FACS data for nasal (A), tracheal (B), bronchial (C) and alveolar (D) epithelial cells are shown. Airway epithelial cells were exposed to 10 μg/ml of TiO2-NP or TiO2-FP, then stained with annexin V-FITC and propidium iodide (PI), and cytotoxicity was measured by FACS. Bronchial and alveolar epithelial cells showed increased fractions of early apoptotic cells after TiO2-NP exposure, while TiO2-FP diverted cells to necrosis. Data shown are representative of 3 independent experiments.