TABLE 10 .

Lab C spiking study: analysis of REO1 genes in rRNA-depleted samples (cell pellet plus mixed-virus spike)

REO1 gene	High spikea (312,550,440)d		Medium spikeb (394,850,748)		Low spikec (354,248,828)
	No. of reads	% genome coverede	No. of reads	% genome coverede	No. of reads	% genome coverede
L1	239,032	100.0	2,265	99.5	22	39.6
L2	34,346	100.0	354	98.2	4	10.1
L3	264,642	100.0	2,762	99.9	23	47.7
M1	156,172	100.0	1,434	99.5	10	40.6
M2	151,276	100.0	1,813	99.8	22	57.6
M3	141,230	100.0	1,384	99.6	4	13.6
S1	83,878	100.0	801	99.5	8	49.9
S2	64,488	100.0	675	99.5	10	42.2
S3	38,088	100.0	442	98.7	10	43.1
S4	49,542	100.0	523	99.5	10	53.4

^aHigh spike, 100 copies per cell.

^bMedium spike, 3 copies per cell.

^cLow spike, 0.1 copy per cell.

^dThe total read number is shown in parentheses.

^ePercentage of viral genome covered by the mapped reads.