Table 3.

Univariate and multivariate Cox Proportional Hazard models of development of HTN during 9-year follow-up

Variables	Univariate models		Multivariate models
	HR (95%CI)	P value	HR (95%CI)	p value
Gender (male)	1.62 (1.46–1.78)	< 0.001	1.33 (1.14–1.56)	< 0.001
Age (years)	1.03 (1.03–1.04)	< 0.001	1.03 (1.02–1.03)	< 0.001
BMI (kg/m2)	1.16 (1.15–1.18)	< 0.001	1.09 (1.06–1.12)	< 0.001
WC (cm)	1.06 (1.05–1.06)	< 0.001	1.01 (1.00–1.02)	0.017
BUN (mmol/L)	1.11 (1.07–1.15)	< 0.001	1.00 (0.96–1.04)	0.967
Cr (μmol/L)	1.00 (1.00–1.01)	< 0.001	1.00 (1.00–1.01)	0.018
FPG (mmol/L)	1.26 (1.21–1.30)	< 0.001	1.10 (1.03–1.18)	0.006
UA (μmol/L)	1.01 (1.00–1.00)	< 0.001	1.00 (1.00–1.00)	0.006
AST (U/L)	1.01 (1.00–1.01)	< 0.001	1.00 (1.00–1.01)	0.648
ALT (U/L)	1.00 (1.00–1.00)	< 0.001	1.00 (1.00–1.00)	0.433
γ-GGT (U/L)	1.00 (1.00–1.01)	< 0.001	1.00 (1.00–1.00)	0.001
TC (mmol/L)	1.28 (1.22–1.34)	< 0.001	1.16 (0.95–1.43)	0.144
TG (mmol/L)	1.29 (1.25–1.33)	< 0.001	1.08 (0.94–1.24)	0.264
HDL-C (mmol/L)	0.86 (0.77–0.97)	0.010	0.96 (0.74–1.25)	0.756
LDL-C (mmol/L)	1.31 (1.24–1.38)	< 0.001	0.84 (0.70–1.02)	0.073
Apo-A1 (g/L)	1.02 (0.86–1.21)	0.812	1.07 (0.86–1.33)	0.562
Apo-B (g/L)	3.47 (2.95–4.09)	< 0.001	1.15 (0.78–1.70)	0.490
eGFR (mL/(min·1.73 m2))	1.00 (0.99–1.00)	< 0.001	1.00 (1.00–1.00)	0.238
TyG		< 0.001		0.013
Quartile 1	1.00 (reference)		1.00 (reference)
Quartile 2	1.38 (1.20–1.59)		1.21 (1.00–1.47)
Quartile 3	2.00 (1.74–2.29)		1.49 (1.16–1.93)
Quartile 4	2.63 (2.31–3.00)		1.53 (1.07–2.19)