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. Author manuscript; available in PMC: 2017 Sep 14.
Published in final edited form as: Neuropharmacology. 2017 Mar 29;119:40–47. doi: 10.1016/j.neuropharm.2017.03.031

Table 2.

Kinetics of mutant GluN1/GluN3A receptors

GluN1-3 3S/D 3S/A S890A S896A S897A
Ipk (pA) 246 ± 87 211 ± 56 312 ± 45 267 ± 63 345 ± 97
Iss (pA) 16 ± 9 36 ± 11 15 ± 2 39 ± 14 32 ± 8
Iss/Ipk 0.06 ± 0.02 0.16 ± 0.04* 0.05 ± 0.01 0.13 ± 0.03* 0.10 ± 0.02
TauD (s) 0.20 ± 0.06 0.24 ± 0.04 0.31 ± 0.05 0.24 ± 0.06 0.32 ± 0.09
*

P < 0.05 relative to WT GluN1-3a Iss/Ipk