Table 2.
Reproductive parameters and F1 litter data.
| Dose (mg/kg/day) | 0 | 1 | 5 | 25 | 100 |
|---|---|---|---|---|---|
| Number of females paired | 15 | 15 | 15 | 15 | 14 |
| Number of females mated | 14 | 15 | 14 | 15 | 11 |
| Number of pregnant females | 14 | 14 | 14 | 14 | 11 |
| Number of females that littered | 15 | 14 | 15 | 14 | 12 |
| Mating index (%)a | 100 | 100 | 100 | 100 | 100 |
| Fertility index (%)b | 100 | 93.3 | 100 | 93.3 | 100 |
| Gestation index (%)c | 100 | 100 | 100 | 100 | 100 |
| Viability index (%)d | 93.7 | 100 | 99.5 | 100 | 90.3 |
| Lactation index (%)e | 99.0 | 100 | 100 | 99.1 | 54.5# |
| Precoital interval (days) | 2.0(1.2)f | 2.0(1.1) | 2.2(1.3) | 2.6(1.8) | 2.5(1.6) |
| Mean gestation length (days) | 18.9(0.3) | 18.8(0.4) | 19.0(0.1) | 19.0(0.3) | 18.9(0.5) |
| Implantations | 11.7(1.5) | 12.1(1.6) | 11.5(2.5) | 12.1(1.9) | 11.2(3.3) |
| Number of pups born | 11.0(2.0) | 11.5(1.5) | 11.3(2.7) | 11.1(1.7) | 11.6(1.6) |
| Number of pups born alive | 11.0(2.0) | 11.5(1.5) | 11.3(2.7) | 11.0(1.8) | 11.4(1.3) |
| Sex ratio (% males) | 52.0(20.6) | 51.6(8.5) | 47.6(15.9) | 40.7(14.6) | 48.8(19.9) |
a
Number copulated/number paired.
b
Number pregnant/number copulated.
c
Number of litters with at least 1 live pup/number of litters.
d
Number of pups alive on day 4/number of pups born alive.
e
Number of live pups on lactation day 21/number of live pups on day 4 post-culling.
f
Data are presented as mean (standard deviation).
#
Significantly different (p < 0.05) from control by Dunnett's test.