Table 3.
F1 in-life parameters.
| Dose (mg/kg/day) | 0 | 1 | 5 | 25 |
|---|---|---|---|---|
| F1 males | 13 | 14 | 15 | 14 |
| Body weight gain (PND 21–40) | 18.0(2.1) | 18.0(2.3) | 17.5(1.5) | 18.2(1.7) |
| Daily food consumption (PND 21–40) | 5.4(0.6) | 5.7(0.5) | 5.4(0.4) | 5.4(0.5) |
| Age at preputial separation achievement | 28.3(1.5) | 27.5(1.2) | 27.3(1.7) | 27.9(1.5) |
| F1 females | 13 | 14 | 14 | 14 |
| Body weight gain (PND 21–40) | 11.2(1.2) | 11.0(1.4) | 11.8(1.2) | 11.2(1.9) |
| Daily food consumption (PND 21–40) | 4.8(0.4) | 4.9(0.4) | 5.1(0.4) | 4.9(0.5) |
| Age at vaginal patency achievement | 29.8(2.2) | 29.4(2.6) | 29.2(2.8) | 30.2(2.2) |
Numbers of animals completing each phase are listed. Data are presented as mean (standard deviation). Units are grams (body weight gain), grams/day (food consumption), and post-natal days (preputial separation or vaginal patency achievement). There were no statistically significant differences (p < 0.05).