Table 5.
P1 organ weights (females).
| Dose (mg/kg/day) | 0 | 1 | 5 | 25 | 100 |
|---|---|---|---|---|---|
| No. examined | (13) | (15) | (15) | (15) | (10) |
| Absolute | |||||
| Terminal body weight | 39.2(2.8) | 40.6(5.7) | 39.9(3.7) | 39.8(4.2) | 35.4(2.9) |
| Liver | 2.809(0.329) | 3.070(0.605) | 3.005(0.418) | 3.048(0.526) | 3.162(0.640) |
| Kidneys | 0.514(0.027) | 0.525(0.090) | 0.516(0.038) | 0.546(0.059) | 0.515(0.051) |
| Ovaries | 0.0316(0.0045) | 0.0370(0.0088) | 0.0342(0.0055) | 0.0355(0.0095) | 0.0244(0.0032)# |
| Uterus | 0.264(0.131) | 0.202(0.068) | 0.198(0.058) | 0.203(0.068) | 0.118(0.069)# |
| Relative | |||||
| Liver | 7.162(0.604) | 7.512(0.774) | 7.510(0.537) | 7.624(0.911) | 8.873(1.341)# |
| Kidneys | 1.316(0.086) | 1.293(0.113) | 1.296(0.081) | 1.376(0.114) | 1.454(0.080)# |
| Ovaries | 0.081(0.012) | 0.093(0.025) | 0.086(0.017) | 0.089(0.023) | 0.069(0.010) |
| Uterus | 0.675(0.334) | 0.515(0.211) | 0.505(0.178) | 0.518(0.198) | 0.332(0.176)# |
Data are presented as mean (standard deviation). Absolute weights are reported in grams; relative weights are reported as percent terminal body weight.
#
Significantly different (p < 0.05) from control by Dunnett's test.