Table 6.

P₁ histopathology of liver.

Dose (mg/kg/day): no. examined	Male					Female
	0(15)	1(15)	5(15)	25(15)	100(15)	0(15)	1(15)	5(15)	25(15)	100(15)
Hypertrophy, hepatocellular	0	0	9	10	15	0	0	13	12	13
Mitotic figures, increased	0	0	0	0	5	0	1	0	1	10
Oval cell hyperplasia	0	0	0	0	15	0	0	0	2	12
Cystic degeneration	0	0	0	0	0	0	0	1	1	7
Single cell necrosis	0	0	0	0	12	2	1	1	1	12
Infiltrate, mononuclear (oval cell associated)	0	0	0	0	15	0	0	0	0	10
Pigment, increased	0	0	0	0	15	0	0	0	0	0