Fig. 3.

Pancreas from a male rat fed 300 ppm APFO (Study 2). (A) Low magnification of acinar cell hyperplasia (H) and acinar cell adenoma (A). Note that both lesions are round to oval, well-circumscribed and are morphologically similar except for their size. Bar = 500 μm. (B and C) Higher magnification of acinar hyperplasia and adenoma, respectively, from (A). Note that the morphologic similarity of the hyperplasia and adenoma, and the similarity of both to the acinar cell hyperplasia present in Fig. 1B from a control rat (mitoses at arrowheads and apoptosis at arrows). Bars = 20 μm.