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. 2014 Nov 28;2:333–340. doi: 10.1016/j.toxrep.2014.11.015

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© 2014 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/).

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Fig. 1 — Photomicrographs of liver sections. Left panels: tissue samples counter stained with hematoxylin-eosin. (A) Control: normal hepatic parenchyma. (B) Advanced HCC: non-cancerous cells (a) and atypical hepatocytes (b). Abnormal hepatic parenchyma was present, with a pseudo-acinar and trabecular growth pattern. (C) Precancerous lesions: low-grade dysplastic nodules (DN) and collagen deposition (black arrows) (Original magnification 40×). Right panels: tissue samples counter stained with picrosirius red. (D) Control: normal hepatic parenchyma. (E) Advanced HCC: intense deposits of fibrosis. (F) Precancerous lesions: moderated deposits of fibrosis (Original magnification 100×).