Skip to main content
. 2014 Nov 15;1:1195–1201. doi: 10.1016/j.toxrep.2014.11.009

Table 2.

Chromosome aberration test of EAHE mycelium using CHO-K1 cells.

Dose S9-Mixture G B D R g b e AFd
Short-term treatment (3 h)
Negative controla − 0 0 0 0 0 0 0 0/200
Positive controlb − 0 0 0 1 1 5 18 25/200*
2.5 − 0 0 0 1 0 0 3 4/200
1.25 − 0 0 0 0 0 0 0 0/200
0.625 − 0 0 0 0 1 0 0 1/200
Negative controla + 0 0 0 0 1 1 0 2/200
Positive controlc + 0 1 2 0 0 8 2 13/200*
2.5 + 0 0 0 0 0 1 0 1/200
1.25 + 0 0 0 0 0 0 1 1/200
0.625 + 0 0 0 0 0 1 0 1/200



Long-term treatment (20 h)
Negative controla − 0 0 0 0 0 0 0 0/200
Positive controlb − 0 0 2 0 2 5 11 20/200*
2.5 − 0 0 0 0 0 0 0 0/200
1.25 − 0 0 0 0 0 0 0 0/200
0.625 − 0 0 0 0 0 0 0 0/200

G: chromosome gap; B: chromosome break; D: dicentric; R: ring; g: chromatid gap; b: chromatid break; e: chromatid exchange.

*

Statistically significant (p < 0.05, Chi-square test) when compared to the control group.

a

Ham's/F-12 Culture medium.

b

6 μM mitomycin C.

c

80 μM cyclophosphamide.

d

Aberration frequency: Number of cells with chromosome aberration in 200 metaphase cells (n/200).