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. 2014 Nov 4;1:1143–1151. doi: 10.1016/j.toxrep.2014.10.023

Fig. 3.

Fig. 3

Activation of NFκB and induction of interferon stimulated genes in Huh7 cells after exposure to SiO2-NPs. (A) Huh7 cells were exposed to 0.05 mg/ml SiO2-NPs for 24 h followed by NFκB activation assay. (B) Huh7 cells were exposed to 0.005 (blank bars), 0.05 (vertical strips) and 0.5 mg/ml (horizontal strips) SiO2-NPs for 24 h followed by the investigation of mRNA level of IRF-9, ISG-15 and IP-10. Shown are the results of three independent experiments. Significant differences with p-value of ≤0.05 are marked with asterisks.