Table 2.

Amount of hydrolysis/oxidation products and β-lyase metabolites of sulfur mustard in samples from four individual patients.^a

Patient (burn degree)	Day after exposure	Urined					Bloode			Exudatef
		TDGc	TDG + TDGOb,c	SBMTEb,c	SBMSE	MSMTESE	SMO	SBMSE	MSMTESE	SMO	TDG	TDGO	SBMSE	MSMTESE
1 (I° 1%)	3	0.48	29.3	78.2	12.7	44.9	D	0.06	0.17
	4	1.30	14.6	50.7	64.7	26.8		NA	NA
	5	1.13	5.11	0.39	7.74	4.93		0.04	0.11	NA
	6	0.26	5.02	0.03	ND	0.58		0.01	0.01
	7	0.30	2.30	0.14	ND	0.08		ND	ND
2 (I° 15% II° 3%)	3	2.30	68.6	6.30	3.76	2.22	D	0.02	0.04	15.5	1080	343	0.06	0.04
	4	2.25	69.5	4.44	14.1	8.73		NA	NA	13.7	1165	428	0.05	0.04
	5	0.44	5.78	0.02	ND	0.14		0.01	0.01	0.74	4430	1605	0.04	0.03
	6	0.30	4.05	0.02	ND	0.08		ND	ND	1.37	5900	1370	0.06	0.03
	7	0.30	11.7	0.12	ND	0.08		ND	ND	NA	NA	NA	NA	NA
3 (I° 7% II° 2%)	3	1.65	54.1	163	183	47.0	D	0.24	0.59	0.12	33.8	4.94	0.44	0.61
	4	4.34	25.9	58.0	151	51.6		NA	NA	0.05	24.9	11.2	0.39	0.55
	5	1.05	3.68	4.53	14.7	19.8		0.05	0.17	0.13	100	18.7	0.25	0.23
	6	1.04	5.58	0.16	ND	1.55		0.01	0.04	0.40	148	25.1	0.10	0.11
	7	0.30	2.20	0.06	ND	0.06		ND	ND	NA	NA	NA	NA	NA
4 (I° 8% II° 2%)	3	1.00	32.2	74.3	128	138	D	0.27	0.47	0.85	2.81	7.22	0.39	0.17
	4	0.90	23.3	49.6	158	76.6		NA	NA	0.73	20.2	7.58	0.38	0.18
	5	1.62	9.44	15.9	32.5	23.8		0.06	0.17	0.16	ND	6.38	0.19	0.09
	6	0.30	5.47	2.0	13.5	10.5		0.03	0.17	0.90	ND	7.08	0.18	0.12
	7	0.30	4.32	1.22	2.14	1.87		0.03	0.05	NA	NA	NA	NA	NA

Abbreviations: ND, not detected; NA, not applicable; D, detected but the amount is below LLOQ which cannot be accurately measured.

^aResults are showed for determinations performed in duplicate or triplicate. The unit of measurement is ng/mL.

^bAfter reduction with TiCl₃.

^cdetected by GC–MS methods.

^dSMO, TDG, TDGO, SBSNAE and SBMTE were not detected or found in the urine samples by HPLC–MS/MS method.

^eTDG, TDGO, SBSNAE and SBMTE were not detected or found in the blood samples by HPLC–MS/MS method.

^fSBSNAE and SBMTE were not found in the exudate samples by HPLC–MS/MS method.