Table 14.

Effect of cleistanthins A and B on absolute organ weight of female Wistar rats (g).

Group	Brain	Heart	Lung	Stomach	Liver	Kidney (L)	Kidney (R)	Mean kidney wt.	Uterus
Control	1.88 ± 0.06	0.59 ± 0.04	1.63 ± 0.06	1.43 ± 0.13	6.06 ± 0.32	0.70 ± 0.03	0.66 ± 0.03	0.68 ± 0.03	3.62 ± 0.35
Cleistanthin A 12.5 mg/kg	1.90 ± 0.24	0.65 ± 0.06	1.70 ± 0.16	1.87 ± 0.25***	6.45 ± 0.56	1.10 ± 0.17***	0.92 ± 0.14***	1.01 ± 0.15***	2.96 ± 0.30*
Cleistanthin A 25 mg/kg	1.66 ± 0.14	0.59 ± 0.04	1.63 ± 0.14	1.56 ± 0.06	6.42 ± 0.27	0.80 ± 0.03	0.75 ± 0.02	0.78 ± 0.03	3.47 ± 0.38
Cleistanthin A 50 mg/kg	1.98 ± 0.06	0.63 ± 0.05	1.59 ± 0.11	1.48 ± 0.131	6.13 ± 0.32	0.85 ± 0.04	0.74 ± 0.03	0.79 ± 0.03	2.86 ± 0.30**
Cleistanthin B 12.5 mg/kg	2.38 ± 0.05***	0.72 ± 0.05**	1.89 ± 0.03**	1.86 ± 0.07***	6.70 ± 0.63	0.93 ± 0.04**	0.90 ± 0.05***	0.92 ± 0.05***	3.24 ± 0.29
Cleistanthin B 25 mg/kg	2.31 ± 0.12***	0.62 ± 0.03	1.89 ± 0.08**	1.76 ± 0.10**	7.37 ± 0.06***	1.11 ± 0.18***	0.90 ± 0.04***	1.00 ± 0.11***	3.78 ± 0.30
Cleistanthin B 50 mg/kg	2.20 ± 0.08**	0.69 ± 0.09	1.85 ± 0.02**	1.99 ± 0.08***	6.25 ± 0.14	0.97 ± 0.05***	0.91 ± 0.04***	0.94 ± 0.05***	3.55 ± 0.45

The values are mean ± SEM; n = 6 in each group; *P < 0.05, **P < 0.01, ***P < 0.001, compared to control. One-way ANOVA followed by Bonferroni test.