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. 2014 Aug 19;1:596–611. doi: 10.1016/j.toxrep.2014.08.006

Table 7.

Effect of cleistanthin A on mortality of rat.

Drug and dose Number of animals died
Description
M (n = 6) F (n = 6)
Control (0.5% CMC) 0 0
Cleistanthin A 12.5 mg/kg 0 0
Cleistanthin A 25 mg/kg 1 0 Male rate died on 14th day
Cleistanthin A 50 mg/kg 0 0
Cleistanthin A 100 mg/kg 2 2 Male rats died on 28th and 30th day and female rats died on 25th and 30th day
Cleistanthin A 200 mg/kg 2 2 Male rats died on 10th and 12th day and female rats died on 7th and 14th day
Cleistanthin A 400 mg/kg 2 3 Male rats died on 4th and 6th day and female rats died on 4th, 5th and 6th day