Table 8.

Effect of cleistanthin B on mortality of rat.

Drug and dose	Number of animals died		Description
	M (n = 6)	F (n = 6)
Control (0.5% CMC)	0	0
Cleistanthin B 12.5 mg/kg	1	1	Male rats died on 70th day and female animal died on 65th day
Cleistanthin B 25 mg/kg	1	0	Male rats died on 82nd day
Cleistanthin B 50 mg/kg	1	3	Male rats died on 80th and female rats died on 52nd, 67th and 72nd day of drug administration
Cleistanthin B 100 mg/kg	2	3	Male rats died on 18th and 25th day of and female rats died on 17th, 23rd and 31th day
Cleistanthin B 200 mg/kg	3	3	Male rats died on 5rd and 9th (2 Nos.) day and female rats died on 4th (2 Nos.) and 7th day
Cleistanthin B 400 mg/kg	5	4	Male rats died on 3rd, 4th (2 Nos.) and 5th (2 Nos.) day and female rats died on 2nd (2 Nos.) and 3rd (2 Nos.) day