Fig. 1.

Effect of Iban on I_K recorded from MDCK cells. (A) Original current traces obtained with or without addition of Iban at −50 mV and a long ramp pulse from−100 to +60 mV with a duration of 1 s at a rate of 0.05 Hz. a: control (black); b: 10 μM Iban (blue); c: 30 μM Iban (red). (B) Summary of the data showing effects of Iban, paxilline, ketamine and Iban plus NaHS on the I_K amplitude measured at the level of +40 mV. Values are means ± SEM for n = 15–18 cells for each group. Iban: 30 μM Iban; Pax: 1 μM paxilline; Ketamine: 100 μM ketamine; NaHS: 100 μM sodium hydrosulfide. ^*Significantly different from control (P < 0.05) and ^#significantly (P < 0.05) different from Iban (30 μM) alone. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)