Fig. 1.

Dose response studies with aqueous curry leaf extract. The rats were fed different doses of Cu LE (ranging from 50 to 300 mg/kg body weight) 1 h before oral administration of piroxicam at 30 mg/kg body weight. (A) Macroscopic view of rat gastric mucosal surface, blue arrow heads are pointing towards pin head ulcer spots. (B) Representative images of H&E stained gastric sections at magnification 400×, black arrow heads are pointing towards regions of mucosal erosion. (C) Bar graphs representing the changes in ulcer index. (D) Representative figure for changes in lipid peroxidation level. (E) Representative figure for changes in reduced glutathione content. All values in (C)–(E) are expressed as mean ± S.E.M. where *P ≤ 0.001 vs. control, **P ≤ 0.001 vs. piroxicam treated animals (one-way ANOVA followed by Scheffe’ multiple comparison test).