. 2014 Nov 7;2:46–55. doi: 10.1016/j.toxrep.2014.11.003

Table 2.

Effect of hesperidin on the levels renal functional markers in control and experimental rats.

Groups	Control	Normal + HDN (80 mg/kg)	Normal + Fe (30 mg/kg)	Fe (30 mg/kg) + HDN (20 mg/kg)	Fe (30 mg/kg) + HDN (40 mg/kg)	Fe (30 mg/kg) + HDN (80 mg/kg)
Urea in serum (mg/dl)	36.64 ± 2.52^a	35.56 ± 2.45^a	63.41 ± 5.33^b	57.72 ± 4.76^c	51.21 ± 4.89^d	43.54 ± 3.96^e
Creatinine in serum (mg/dl)	0.46 ± 0.05^a	0.45 ± 0.05^a	0.92 ± 0.09^b	0.84 ± 0.06^c	0.76 ± 0.04^d	0.55 ± 0.05^e
Creatinine clearance (ml/min)	0.29 ± 0.05^a	0.29 ± 0.05^a	0.10 ± 0.03^b	0.14 ± 0.03^c	0.20 ± 0.04^d	0.23 ± 0.04^e
Hemoglobin (g/dl blood)	10.90 ± 0.71^a	11.18 ± 0.93^a	6.60 ± 0.63^b	7.70 ± 0.50^c	8.61 ± 0.58^d	10.74 ± 0.65^e

Values are mean ± SD for 6 rats in each group. Values are not sharing a common superscript letter (a, b, c, d and e) differ significantly at p < 0.05 (DMRT). HDN—hesperidin; Fe—ferrous sulfate.