Table 6.
Changes in the levels of non-enzymatic antioxidants in control and experimental rats.
| Groups | Control | Normal + HDN (80 mg/kg) | Normal + Fe (30 mg/kg) | Fe (30 mg/kg) + HDN (80 mg/kg) |
|---|---|---|---|---|
| GSH | ||||
| Plasma | 19.93 ± 1.31a | 20.07 ± 1.71a | 15.22 ± 1.19b | 18.07 ± 1.11c |
| Liver | 4.20 ± 0.21a | 4.29 ± 0.30a | 2.83 ± 0.16b | 3.52 ± 0.23c |
| Kidney | 2.44 ± 0.19a | 2.57 ± 0.19a | 1.22 ± 0.18b | 1.77 ± 0.23c |
| Vitamin C | ||||
| Plasma | 1.86 ± 0.08a | 1.94 ± 0.11a | 1.54 ± 0.06b | 1.70 ± 0.07c |
| Liver | 1.59 ± 0.05a | 1.62 ± 0.05a | 1.14 ± 0.04b | 1.44 ± 0.06c |
| Kidney | 0.94 ± 0.08a | 1.01 ± 0.09a | 0.61 ± 0.06b | 0.82 ± 0.07c |
| Vitamin E | ||||
| Plasma | 1.34 ± 0.07a | 1.39 ± 0.12a | 0.90 ± 0.07b | 1.21 ± 0.09c |
| Liver | 0.78 ± 0.06a | 0.83 ± 0.07a | 0.49 ± 0.04b | 0.62 ± 0.05c |
| Kidney | 0.69 ± 0.05a | 0.73 ± 0.05a | 0.46 ± 0.01b | 0.55 ± 0.03c |
Values are mean ± SD for 6 rats in each group. Values are not sharing a common superscript letter (a, b and c) differ significantly at p < 0.05 (DMRT). The level of GSH was expressed as mg/dl plasma and μg/mg tissue protein; The levels of vitamin C and vitamin E were expressed as mg/dl plasma and μM/mg tissue. HDN—hesperidin, Fe—ferrous sulfate.