Fig. 7.

Effect of curcumin post-treatment on cell proliferation markers in B(a)P-treated mice (experiments 1 and 2). Representative blot and relative levels of (A) PCNA in liver at 24, 72 and 120 h, (B) PCNA and Cyclin D1 in lungs at 24, 72 and 120 h, (C) PCNA in liver at 7, 14 and 28 days, and (D) PCNA in lungs at 7, 14 and 28 days measured in total cell lysates prepared from mouse tissues as analyzed by immunoblotting using specific antibodies, respectively. β-Actin was used as the loading control. Data represent mean ± SE of three observations. ‘*’ significant when compared to BP_{(+24 h)} subgroup; ‘^#’ significant when compared to respective time-matched controls (p ≤ 0.5, ANOVA followed by Bonferroni's test, p ≤ 0.05).