Fig. 6.

TNFα, IL-6, IL-10, IFNγ and IL-4 cytokine release in cells isolated from 11 weeks old NOD offspring continuously exposed to BPA and phthalates (group mean ± SEM, n = 8). ConA-induced (A) and LPS-induced (B) cytokine release from splenocytes. (C) LPS-induced cytokine release from pancreatic draining lymph node cells. (D) LPS-induced cytokine release from pancreatic islets. All cytokines were measured for all cell types, but are not shown when the cytokine levels in general were below detection limits. *Significant differences from the control group, p < 0.05.