. 2015 May 12;2:737–747. doi: 10.1016/j.toxrep.2015.05.007

Table 2.

Effect of oral administration of AFB₁ alone or in combination with Q and/or CNPs on serum cytokines, procollagen III and nitric oxide.

Parameter groups	CEA (ng/ml)	TNF-α (ng/l)	IL-1α (ng/ml)	Procollagen III (μg/l)	NO (μmol/l)
Control	2.75 ± 0.34^a	57.3 ± 2.95 ^a	0.75 ± 0.03^a	2.6 ± 0.12^a	34.74 ± 1.93^a
AFB₁	9.54 ± 1.51^b	96.42 ± 2.33^b	4.24 ± 0.93^b	8.96 ± 0.86^b	85.83 ± 2.44^b
CNPs-LD	2.55 ± 0.62^a	55.23 ± 2.63^a	0.74 ± 0.02^a	2.55 ± 0.21^a	33.86 ± 2.45^a
CNPs-HD	2.66 ± 0.52^a	56.72 ± 2.47^a	0.77 ± 0.04^a	2.59 ± 0.23^a	34.62 ± 2.09^a
Q	2.71 ± 0.33^a	57.22 ± 2.62^a	0.76 ± 0.04^a	2.89 ± 0.31^a	35.64 ± 1.88^a
CNPs-LD + Q	2.77 ± 0.37^a	56.92 ± 1.94^a	0.77 ± 0.05^a	2.49 ± 0.47^a	35.43 ± 2.53^a
CNPs-HD + Q	2.79 ± 0.64^a	58.1 ± 3.42^a	0.77 ± 0.07^a	2.58 ± 0.41^a	35.82 ± 2.94^a
CNPs-LD + AFB₁	4.93 ± 0.86^c	67.53 ± 3.63^c	2.99 ± 0.75^c	5.74 ± 1.22^d	57.83 ± 2.44^c
CNPs-HD + AFB₁	4.22 ± 0.77^c	62.75 ± 2.96^d	2.53 ± 0.84^c	4.96 ± 1.31^d	55.83 ± 2.48^c
Q + AFB₁	4.76 ± 1.22^c	64.83 ± 2.67^e	2.67 ± 0.45^c	4.99 ± 1.08^d	59.84 ± 2.45^c
CNPs-LD + Q + AFB₁	3.95 ± 0.93^d	60.42 ± 1.69^d	1.87 ± 0.54^e	3.83 ± 0.89^e	43.82 ± 2.94^d
CNPs-HD + Q + AFB₁	2.83 ± 0.92^a	58.52 ± 2.66^a	1.22 ± 0.23^e	2.83 ± 0.77^a	38.32 ± 2.76^e

Within each column, means superscript with different letters are significantly different (P ≤ 0.05).