Table 6.
Biochemical parameters after a 28-day treatment with the methanol extract of stem bark of Amphimas pterocarpoides in male Wistar rats.
| Parameters | Control |
A. pterocarpoides (mg/kg BW) |
Satellite groups |
|||
|---|---|---|---|---|---|---|
| 150 | 300 | 600 | Control SAT | 600 SAT | ||
| TG (mg/dL) | 95.92 ± 21.39 | 124.25 ± 9.14 | 79.64 ± 18.85 | 69.73 ± 11.98 | 105.06 ± 15.80 | 103.47 ± 3.91 |
| TC (mg/dL) | 76.36 ± 4.63 | 73.40 ± 5.06 | 74.38 ± 5.37 | 79.05 ± 9.19 | 77.13 ± 4.76 | 83.72 ±13.04 |
| HDL-C (mg/dL) | 31.86 ± 2.39 | 24.78 ± 0.70** | 22.36 ± 2.03** | 21.48 ± 2.27** | 13.92 ± 0.98 | 15.21 ± 1.77 |
| ALT (U/L) | 96.56 ± 6.64 | 93.23 ± 2.97 | 107.24 ± 4.58 | 116.96 ± 4.58 | 111.20 ± 4.58 | 99.16 ± 4.91 |
| AST (U/L) | 105.79 ± 6.39 | 106.54 ± 3.30 | 108.86 ± 1.26 | 115.91 ± 3.83 | 111.00 ± 2.92 | 108.67 ± 1.92 |
| TB (mg/dL) | 0.2 ± 0.02 | 0.19 ± 0.03 | 0.22 ± 0.03 | 0.45 ± 0.11** | 0.24 ± 0.02 | 0.24 ± 0.02 |
| TP (g/dL) | 1.39 ± 0.04 | 1.31 ± 0.02 | 1.35 ± 0.05 | 1.46 ± 0.07 | 1.43 ± 0.10 | 1.17 ± 0.02** |
| TC/HDL-C | 2.43 ± 0.18 | 2.97 ± 0.24 | 3.44 ± 0.37 | 3.70 ± 0.24* | 5.64 ± 0.47 | 5.45 ± 0.72 |
TG: triglycerides; TC: total cholesterol; HDL-C: high density lipoprotein cholesterol; ALT: alanine transaminase; AST: aspartate transaminase; TB: total bilirubin; TP: total protein. Control SAT: satellite control treated with vehicle; 600 SAT: satellite of top dose treated with AP at 600 mg/kg BW.
Data are represented as mean ± SEM (n = 5).
*p < 0.05 and **p < 0.01 significantly different compared to control groups.