Table 7.
Biochemical parameters after a 28-day treatment with the methanol extract of stem bark of Amphimas pterocarpoides in female Wistar rats.
| Parameters | Control |
A. pterocarpoides (mg/kg BW) |
Satellite groups |
|||
|---|---|---|---|---|---|---|
| 150 | 300 | 600 | Control SAT | 600 SAT | ||
| TG (mg/dL) | 68.65 ± 6.69 | 93.48 ± 4.96 | 92.96 ± 9.82 | 84.66 ± 8.72 | 66.64 ± 3.05 | 64.54 ± 8.00 |
| TC (mg/dL) | 60.87 ± 3.84 | 61.09 ± 8.91 | 60.20 ± 7.49 | 54.01 ± 3.55 | 63.92 ± 10.71 | 67.61 ± 12.63 |
| HDL-C (mg/dL) | 22.04 ± 1.19 | 18.80 ± 0.83 | 22.43 ± 1.37 | 22.33 ± 0.61 | 10.33 ± 0.87 | 10.71 ± 1.69 |
| ALT (U/L) | 105.4 ± 1.29 | 100.13 ± 3.70 | 104.73 ± 3.13 | 101.80 ± 2.58 | 115.72 ± 1.86 | 106.87 ± 4.04 |
| AST (U/L) | 121.2 ± 3.72 | 129.64 ± 5.71 | 114.34 ± 4.88 | 112.99 ± 2.98 | 108.46 ± 4.36 | 112.60 ± 3.93 |
| TB (mg/dL) | 0.3 ± 0.02 | 0.3 ± 0.02 | 0.3 ± 0.02 | 0.34 ± 0.02 | 0.26 ± 0.02 | 0.29 ± 0.03 |
| TP (g/dL) | 1.47 ± 0.05 | 1.52 ± 0.08 | 1.44 ± 0.05 | 1.48 ± 0.04 | 1.29 ± 0.07 | 1.07 ± 0.07 |
| TC/HDL-C | 2.78 ± 0.17 | 3.24 ± 0.45 | 2.71 ± 0.34 | 2.42 ± 0.13 | 6.71± 1.64 | 7.88 ± 3.01 |
TG: triglycerides; TC: total cholesterol; HDL-C: high density lipoprotein cholesterol; ALT: alanine transaminase; AST: aspartate transaminase; TB: total bilirubin; TP: total protein. Control SAT: satellite control treated with vehicle; 600 SAT: satellite of top dose treated with AP at 600 mg/kg BW.
Data are represented as mean ± SEM (n = 5).
*p < 0.05 and **p < 0.01 significantly different from control groups.