Table 2.
Incidence of chronic progressive nephropathy in the kidneys of female rats treated with either 0 (control), 1, 50 or 500 mg/kg of ammonium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)-propanoate for 12 months, N = 10.
| Incidences and severity of chronic progressive nephropathy in the kidneys of female rats: interim sacrifice | ||||
|---|---|---|---|---|
| Dose level (mg/kg) | 0 | 1 | 50 | 500 |
| Nephropathy, chronic progressive | 6 | 4 | 6 | 9 |
| -Minimal | 5 | 3 | 4 | 3 |
| -Mild | 0 | 1 | 2 | 6 |
| -Moderate | 1 | 0 | 0 | 0 |