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. 2014 Jul 25;1:474–489. doi: 10.1016/j.toxrep.2014.07.008

Table 1.

EC50 values (μM) of pesticides alone on Caco-2 cells upon 3, 7, and 10 days-period of exposure. Caco-2 cells were exposed to DTM, FNT, FPN, LCT, and TBZ either alone or as a mixture of the five for 3, 7 and 10 days at concentrations ranging from 0.1 to 100 μM. After exposure, cell viability was assessed by MTT assay and effect concentrations 50% (EC50) were calculated according to the dose response curves in Fig. 1 as described in Section 2.

Time (days) EC50 (μM)a
DTM FNT FPN LCT TBZ
3 191.0 ± 5.5 31.6 ± 0.7 24.1 ± 0.4 72.9 ± 2.7 571.1 ± 51.0
7 136.4 ± 10.7 25.6 ± 0.8 21.6 ± 0.5 74.3 ± 4.8 471.3 ± 37.6
10 111.9 ± 3.3 21.3 ± 0.5 18.1 ± 0.5 59.5 ± 2.3 429.4 ± 24.5
a

Mean ± SEM of three independent experiments.