Table 1.
Survival of mice treated orally with TPT (0, 1.875, 3.75, 7.5, 15 mg/kg bw/day) on postnatal days (PND) 15–45.
| Pups alive | TPT (mg/kg bw/day po) |
||||
|---|---|---|---|---|---|
| 0 | 1.875 | 3.75 | 7.5 | 15 | |
| Females | |||||
| PND 15, N (%) | 23 (100) | 22 (100) | 21 (100) | 27 (100) | 21 (100) |
| PND 45, N (%) | 23 (100) | 22 (100) | 21 (100) | 26 (96.3)a | 4 (19)a,b |
| Males | |||||
| PND 15, N (%) | 26 (100) | 26 (100) | 24 (100) | 27 (100) | 26 (100) |
| PND 45, N (%) | 26 (100) | 26 (100) | 24 (100) | 25 (92.6)a | 5 (19.2)a,b |
a
All deaths occurred between PND 21 (weaning) and PND 25.
b
Differ (chi-square test, p < 0.05) from other group survival rates.