Fig. 6.

Effect of naringenin on transcript and protein levels of caspase-3/9 and enzymatic activity of caspase-3. (a) Shows activation of caspase-3 and caspase-9 as evident from the appearance of its cleaved product. (b) Shows m-RNA level of apoptotic genes-caspase-3 and caspase-9 using GAPDH as internal control. Densitometry shows the relative intensity normalized to internal control, (c) shows caspase-3 enzymatic activity of control and treated rats. Results are shown as mean ± S.E. # Denotes significant difference compared with control values and *P < 0.05, **P < 0.01 and ***P < 0.001 denotes significant difference compared with treated rats.