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. 2014 Nov 7;1:1133–1142. doi: 10.1016/j.toxrep.2014.10.014

Table 2.

Comparison of predictive performances.

Method Target direction Average over 10-fold cross validation
Total TP FN FP TP Hold Accuracy (%) Sensitivity (%) Specificity (%)
CBA Inc 14.9 4.4 1.1 1.4 8 83 82 85
LDA Inc 14.9 2.7 1 2.8 8.4 75 72 75
CBA-DR Inc 14.9 4.4 0 1.4 0.8 8.3 79 100 29
CBA Dec 14.9 0.2 0.7 1.4 12.6 86 22 90
LDA Dec 14.9 0.2 3.3 0.7 10.7 73 6 95
CBA-DR Dec 14.9 0 0.7 0 12.6 1.6 95 0 100

Predictive performance of classifiers was compared among CBA, LDA, CBA-DR with 10-fold cross validation.

Target direction: a classifier was built for whether increased (Inc) or decreased (Dec) relative liver weight. Total: average number of total records in a test set of each trial in a cross validation. TP: average number of true positive records in a test set. FN: average number of false negative records in a test set. FP: average number of false positive records in a test set. TN: average number of true negative records in a test set. Hold: average number of records in a test set that did not match any rules except the default rule (only for CBA-DR).

Note that accuracy, sensitivity and specificity for the CBA-DR method were calculated excluding ‘hold’ samples. Totals are not integers here, as the number of records in the original dataset was 149 and thus cannot be divided by 10, the number of trials in the cross validation.