Table 2.
Mean ± SD residue concentrations of zearalenone (ZEA), a-zearalenone (α-ZOL) and b-zearalenone (β-ZOL) in various tissues following a single oral administration at 1.2 mg/kg bw of ZEA in broiler chickens (n = 5).
| Time (h) | ZEA and it major metabolites concentration (ng/g) |
||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Liver |
Kidney |
Small intestine |
Muscle |
Excreta |
|||||||||||
| ZEA | α-ZOL | β-ZOL | ZEA | α-ZOL | β-ZOL | ZEA | α-ZOL | β-ZOL | ZEA | α-ZOL | β-ZOL | ZEA | α-ZOL | β-ZOL | |
| 1 | 3.52 ± 1.9 | 105.2 ± 43.8 | 30.9 ± 13.7 | 3.55 ± 1.5 | 77.99 ± 23.1 | 36.6 ± 9.1 | 114.7 ± 13.1 | 626.1 ± 135.6 | 198.3 ± 60.2 | ND | 2.55 ± 0.2 | 2.40 ± 0.7 | 218.6 ± 20.1 | 399.7 ± 45.1 | 385.6 ± 25.2 |
| 3 | ND | 47.54 ± 24.1 | 37.3 ± 6.9 | ND | 11.28 ± 1.3 | 26.7 ± 6.8 | ND | 200.8 ± 48.5 | 103.9 ± 12.2 | ND | ND | ND | 199.8 ± 20.8 | 468.3 ± 67.8 | 338.1 ± 28.4 |
| 9 | ND | 31.09 ± 12.3 | 25.0 ± 6.6 | ND | 6.76 ± 3.0 | 16.6 ± 4.5 | ND | 91.6 ± 15.1 | 65.0 ± 11.6 | ND | ND | ND | 264.8 ± 27.8 | 1164.9 ± 78.1 | 209.7 ± 17.1 |
| 12 | ND | 7.84 ± 3.3 | 24.4 ± 2.1 | ND | 1.63 ± 0.3 | 4.8 ± 1.8 | ND | 24.6 ± 11.1 | 26.2 ± 6.1 | ND | ND | ND | 114.3 ± 58.2 | 1286.5 ± 144 | 119.4 ± 17.2 |
ND, not detected.