Table 2.
Effect of ADW on non-enzymic antioxidants during BPA induced toxicity in HepG2 cells. Values are Mean ± SEM of three independent experiments carried out in triplicates.
| Groups | GSH (nmol/mg protein) | GSSG (nmol GSH equiv/mg protein) | GSH/GSSG ratio |
|---|---|---|---|
| Control | 78.45 ± 2.22* | 9.58 ± 1.35* | 8.18 |
| Antimycin A (10 μM) | 18.28 ± 3.15** | 33.97 ± 0.98** | 0.53 |
| BPA (100 nM) | 26.64 ± 4.12** | 14.68 ± 2.32 | 1.81 |
| BPA (100 nM) + vitamin E (25 μM) | 64.45 ± 2.22* | 14.58 ± 1.35 | 4.42 |
| BPA (100 nM) + ADW (100 μg/ml) | 68.89 ± 5.19* | 11.23 ± 3.68* | 5.94 |
**
Statistically significant at P < 0.05 compared to control.
*
Statistically significant at P < 0.05 compared to BPA.