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. 2014 Jul 2;1:1004–1012. doi: 10.1016/j.toxrep.2014.06.008

Table 3.

Effect of ADW on antioxidant enzymes catalase, glutathione peroxidase and superoxide dismutase activity during BPA induced toxicity in HepG2 cells. Values are Mean ± SEM of three independent experiments carried out in triplicates.

Groups Catalasea Glutathione peroxidiseb Superoxide dismutasec
Control 1.45 ± 0.18* 28.68 ± 1.35* 45.58 ± 1.56*
Antimycin A (10 μM) 0.58 ± 0.05** 11.57 ± 0.98** 20.97 ± 1.51**
BPA (100 nM) 0.48 ± 0.10** 16.58 ± 1.68** 28.28 ± 1.98**
BPA (100 nM) + vitamin E (25 μM) 0.84 ± 0.12* 23.68 ± 1.32* 35.64 ± 3.11*
BPA (100 nM) + ADW (100 μg/ml) 0.96 ± 0.09* 20.67 ± 1.12* 29.15 ± 2.61
**

Statistically significant at P < 0.05 compared to control.

*

Statistically significant at P < 0.05 compared to BPA.

a

μmol of H2O2 decomposed/min/mg protein.

b

μmol of NADPH oxidized/min/mg protein.

c

Units/mg protein.