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. 2015 Oct 19;2:1423–1433. doi: 10.1016/j.toxrep.2015.10.006

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© 2015 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 2 — Effects of 4-NP (mg/k b. wt) on oxidative stress-related genes expression of experimental rat livers ((A) SOD1, (B) GPx, (C) HSP70). Apoptotic-related genes ((D) Bax, (E) Bcl-2, (F) Casp-9). Hepatotoxicity-related genes ((G) Fas, (H) FasL, (I) TNF-α). The housekeeping gene β-actin is used as an internal positive control. The relative expression of target genes is calculated using 2^−ΔΔCt. Error bars represent the standard deviation. Significant difference:*p < 0.05, **p < 0.01 versus control group. n = 6.