Table 1.

Grading and staging of histopathological of liver steatosis.

Grade	Histological characteristics
1-Mild	Steatosis: predominantly macrovesicular
	Ballooning: occasionally observed
	Lobular inflammation: scattered and mild acute inflammation
2-Moderate	Steatosis: any degree usually mixed macrovesicular and microvesicula
	Ballooning: obvious and present in centrilobular zone
	Lobular inflammation: associated with ballooned hepatocytes
3-Severe	Steatosis: typically involves >66% of lobules
	Ballooning: predominantly, marked in centrilobular zone
	Lobular inflammation: scattered acute and chronic inflammation

According to Brunt et al. grading and staging system for NASH [7].