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. 2014 Aug 20;1:554–561. doi: 10.1016/j.toxrep.2014.08.004

Table 3.

Effect of different doses of imidacloprid on biochemical parameters of liver functions in mice. Administration of pesticides, imidacloprid administered orally with different concentration indicates clinical signs of intoxication.

Parameter Control
(Day 0)
0 (mg/kg/day)
Experimental 1
(Day 5)
5 (mg/kg/day)
Experimental 2
(Day 10)
10/mg/kg/day
Experimental 3
(Day 15)
15 (mg/kg/day)
SGOT (U/l) 45.53 ± 2.70 42.00 ± 2.47*** 43.52 ± 2.42*** 55.38 ± 3.50***
SGPT (U/l) 35.20 ± 2.55 34.65 ± 2.18** 32.30 ± 2.22** 40.63 ± 3.31***
ALP (U/l) 176.5 ± 2.58 178.3 ± 2.16* 179.7 ± 2.16** 185.5 ± 3.50***
TBIL (mg/dl) 0.30 ± 0.011 0.29 ± 0.009*** 0.31 ± 0.012*** 0.36 ± 0.011***

Each value represents the mean ± SD for 12 mice with p value (p < 0.05).

*

Significant difference (P < 0.05).

**

Very significant.

***

Highly significant difference from control (p < 0.01).